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Melanoma


MATCH: Molecular analysis for therapy choice. Targeted therapy directed by genetic testing in treating patients with advanced refractory solid tumors or lymphoma.  EAY131 (NCT02465050)  (MBMC Contact: Missy Kuhn 314-996-5868) 

Randomized Phase III trial of mematine and whole-brain radiotherapy with or without hippocampal avoidance in patients with brain metastases  NRG-CC001 (NCT02360215 )  (MBMC Contact:  Diana Christian 314-996-5888)  (Requires radiation oncologist to undergo training and specialized MRIs - approved at MBMC)

Phase III randomized trial comparing high dose interferon or Ipilimumab to MK-3475 (pembrolizumab) in patients with high risk resected melonoma 
S1404 (NCT02506153)  (MBMC Contact:  Missy Kuhn 314-996-5868Step 1 closing 8/15/17

Randomized Phase III Trial of Dabrafenib + Trametinib followed by Ipilimumab + Nivolumab at Progression Versus Ipilimumab + Nivolumab follwed by Dabrafenib + Trametinib at Progression in Patients with Advanced BRAFV600 Mutant Melanoma  EA6134 (NCT02224781)  (MBMC Contact: Missy Kuhn 314-996-5868)

Ipilimumab With or Without Bevacizumab in Treating Patients With Stage III-IV Melanoma That Cannot Be Removed by Surgery
   (Ipilimumab and Bevacizumab Provided) ECOG E3612 (NCT01950390) (MBMC Contact: Missy Kuhn 314-996-5868

Dabrafenib and Trametinib in Treating Patients With Stage III-IV BRAF Mutant Melanoma That Cannot be Removed by Surgery
 (Dabrafenib and Trametinib Provided)
SWOG S1320 (NCT02196181)  (MBMC Contact: Missy Kuhn 314-996-5868)

Randomized phase II/III study of nivolumab plus ipilimumab plus sargramostim versis nivolumab plus ipilimumab in patients with unresectable stage III or stage IV melanoma
 ECOG-ACRIN EA6141  (NCT02339571)   (MBMC Contact:  Missy Kuhn 314-996-5868 Accrual suspended effective 6/23/17.





Lymphoma Cancer Trials in St. Louis, MO
 
 

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